Kam Ming Ko Selected Research

schizandrin B

1/2016	Schisandrin B: A Double-Edged Sword in Nonalcoholic Fatty Liver Disease.
1/2016	A Naturally-Derived Compound Schisandrin B Enhanced Light Sensation in the pde6c Zebrafish Model of Retinal Degeneration.
1/2016	Correction: A Naturally-Derived Compound Schisandrin B Enhanced Light Sensation in the pde6c Zebrafish Model of Retinal Degeneration.
9/2015	Schisandrin B induces an Nrf2-mediated thioredoxin expression and suppresses the activation of inflammasome in vitro and in vivo.
1/2015	Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling.
1/2012	Schisandrin B as a hormetic agent for preventing age-related neurodegenerative diseases.
8/2011	Prevention of scopolamine-induced memory deficits by schisandrin B, an antioxidant lignan from Schisandra chinensis in mice.
1/2011	(-)Schisandrin B ameliorates paraquat-induced oxidative stress by suppressing glutathione depletion and enhancing glutathione recovery in differentiated PC12 cells.
11/2009	Schisandrin B stereoisomers protect against hypoxia/reoxygenation-induced apoptosis and associated changes in the Ca(2+)-induced mitochondrial permeability transition and mitochondrial membrane potential in AML12 hepatocytes.
7/2008	Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, and protects against cerebral ischemia/reperfusion injury in rats.

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Kam Ming Ko Research Topics

Disease

9	Reperfusion Injury 08/2011 - 01/2003
8	Hypoxia (Hypoxemia) 07/2014 - 05/2008
7	Ischemia 01/2013 - 01/2003
5	Myocardial Ischemia (Ischemic Heart Diseases) 05/2010 - 11/2004
4	Inflammation (Inflammations) 09/2020 - 01/2015
3	Coronary Disease (Coronary Heart Disease) 08/2011 - 02/2011
2	Weight Loss (Weight Reduction) 07/2020 - 01/2015
2	Retinal Degeneration 01/2016 - 01/2016
2	Brain Ischemia (Cerebral Ischemia) 07/2012 - 07/2008
2	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2012 - 01/2012
2	Atherosclerosis 08/2011 - 04/2011
1	Rhinitis 09/2020
1	Asthma (Bronchial Asthma) 09/2020
1	Allergic Rhinitis 09/2020
1	Body Weight (Weight, Body) 07/2020
1	Obesity 07/2020
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2020
1	Tourette Syndrome (Tourette's Syndrome) 01/2019
1	Non-alcoholic Fatty Liver Disease 01/2016
1	Edema (Dropsy) 01/2016
1	Peritonitis 09/2015
1	Chronic Fatigue Syndrome (Myalgic Encephalomyelitis) 01/2015
1	Yang Deficiency (Xu, Yang) 01/2015
1	Carcinoma (Carcinomatosis) 07/2013
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 07/2013
1	Stroke (Strokes) 07/2012
1	Neuroblastoma 07/2012
1	Huntington Disease (Huntington's Disease) 05/2012
1	Necrosis 05/2012
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2012
1	Dementia (Dementias) 08/2011
1	Memory Disorders (Memory Loss) 08/2011
1	Myocardial Infarction 02/2011
1	Pheochromocytoma 01/2011
1	Parkinson Disease (Parkinson's Disease) 01/2011
1	Neoplasms (Cancer) 09/2009
1	Hepatitis 11/2004

Drug/Important Bio-Agent (IBA)

13	schizandrin BIBA 01/2016 - 01/2003
9	AntioxidantsIBA 01/2019 - 10/2005
8	Glutathione (Reduced Glutathione)IBA 07/2014 - 01/2003
7	Adenosine Triphosphate (ATP)IBA 09/2015 - 01/2003
4	Caspase 3 (Caspase-3)IBA 07/2013 - 05/2008
4	Danshen-GegenIBA 01/2012 - 02/2011
3	Pharmaceutical PreparationsIBA 03/2012 - 05/2008
2	Protein Kinases (Protein Kinase)IBA 01/2015 - 09/2009
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 05/2012 - 02/2006
2	schizandrinIBA 11/2009 - 05/2008
2	Cytochromes c (Cytochrome c)IBA 11/2009 - 05/2008
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2009 - 05/2008
2	Emodin (Archin)IBA 08/2006 - 10/2005
2	Oleanolic AcidIBA 08/2006 - 02/2006
1	Immunoglobulin E (IgE)IBA 09/2020
1	Anti-Asthmatic Agents (Antiasthmatic Drugs)IBA 09/2020
1	Anti-Allergic Agents (Antiallergic Agents)IBA 09/2020
1	OvalbuminIBA 09/2020
1	Uncoupling Protein 3IBA 07/2020
1	TriterpenesIBA 07/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019
1	CarrageenanIBA 01/2016
1	Nonesterified Fatty Acids (NEFA)IBA 01/2016
1	aluminum sulfate (alum)IBA 09/2015
1	gamma-sitosterol (beta-sitosterol)IBA 01/2015
1	Adenosine Monophosphate (AMP)IBA 01/2015
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2015
1	EnzymesIBA 01/2015
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2015
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 07/2013
1	Ursolic AcidIBA 01/2013
1	Amyloid (Amyloid Fibrils)IBA 07/2012
1	Proteins (Proteins, Gene)FDA Link 07/2012
1	DNA (Deoxyribonucleic Acid)IBA 07/2012
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 05/2012
1	Oxidoreductases (Dehydrogenase)IBA 05/2012
1	Caspase 9IBA 05/2012
1	Pyruvic Acid (Pyruvate)IBA 05/2012
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2012
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 03/2012
1	Methanol (Carbinol)IBA 01/2012
1	Scopolamine (Hyoscine)FDA Link 08/2011
1	Acetylcholine (Acetylcholine Chloride)FDA Link 08/2011
1	LignansIBA 08/2011
1	Protein Kinase CIBA 04/2011
1	U 0126 (UO 126)IBA 04/2011
1	HerbicidesIBA 01/2011
1	ParaquatIBA 01/2011
1	Gentamicins (Gentamicin)FDA LinkGeneric 02/2008
1	Buthionine SulfoximineIBA 02/2006
1	alpha-Tocopherol FDA Link 02/2006
1	phoroneIBA 02/2006
1	Thioctic Acid (Lipoic Acid)IBA 02/2006
1	DDBIBA 08/2005
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 11/2004

Therapy/Procedure

1	Phytotherapy (Herbal Therapy) 01/2015
1	Therapeutics 09/2009
1	Radiotherapy 09/2009